Shandong Province Science and Technology Front to Aid Epidemic Prevention and Control Work
Release time:
2020-02-24
Since the situation, the scientific and technological front of Shandong Province has resolutely implemented the deployment requirements of the central and provincial party committees and governments, acted quickly, took the initiative, actively contributed to the epidemic prevention work of scientific and technological strength, raced against time, competed with the disease, and helped win the epidemic prevention and control war.
The science and technology departments of 1. cities acted quickly to organize the first-line scientific and technological innovation and services for diagnosis and treatment.
Jinan Science and Technology Bureau in-depth tapping potential, guiding the region's high-tech enterprises to strengthen scientific research, a large number of scientific research results rushed to Hubei, applied to the new crown pneumonia epidemic prevention and control front line. Jinan High-tech Zone Enterprise Akwei Bio formed an 8-person innovation team to sequence the whole genome of the new coronavirus, to find the best combination of primers and probes, and developed the province's first RT-PCR nucleic acid detection kit based on the "2019-nCoV" gene sequence.
The Qingdao Municipal Science and Technology Bureau has mobilized many high-tech enterprises to take action. Qingdao Hantang Biology Company completed the development of a universal nucleic acid detection kit that can quickly determine suspected patient samples within 1 hour in only 3 days. The first batch of test kit samples were sent to Wuhan as soon as possible. As a well-known molecular diagnostic POCT (instant detection) company in China, Qingdao Ned Biological Company launched the first 30-minute nucleic acid quick detection solution in China and trial-produced kits to greatly improve the efficiency of virus quick detection. 20000 sets of goggles and 5300 disposable protective masks produced by Qingdao Yum Brands Medical and Health Products Co., Ltd. were airlifted to Wuhan on the evening of January 27. Qingdao Huaren Pharmaceutical Company mobilized all urgently and donated 50 tons of medical materials arrived in Wuhan on January 30 to provide guarantee for Wuhan to fight the epidemic.
The Weifang Municipal Science and Technology Bureau, in accordance with the principle of "special affairs and special handling", urgently launched a special scientific and technological research project for the prevention and control of the new coronavirus pneumonia epidemic, organized scientific and technological personnel to combine scientific research with clinical and actual combat, carried out coordinated scientific and technological emergency research for epidemic prevention and control, and focused on improving the integration capability of advanced and applicable front-line technologies to solve urgent problems such as rapid detection and treatment of new coronary pneumonia. The colloidal gold method and immune chromatography new coronavirus antibody detection kit developed by Weifang Kanghua Biological Company have passed the inspection of relevant national departments.
In order to help science and technology enterprises alleviate the difficulties caused by the epidemic, Weihai Science and Technology Bureau has accelerated the allocation of the first batch of municipal science and technology special funds totaling 59.5131 million yuan in 2020, involving more than 500 science and technology enterprises. It has also opened a green channel, optimized credit policies, further strengthened financial support, and helped enterprises alleviate the shortage of liquidity funds in the resumption of work and production in conjunction with 17 cooperative banks such as Weihai Branch of Bank of China and Agricultural Bank of China.
Yantai Municipal Science and Technology Bureau quickly launched the new crown pneumonia epidemic prevention and control emergency research special. Yantai Baoyuan Purification Co., Ltd. has independently developed a medical ultra-low resistance return air purification device, and its main indicators such as bacteria filtration efficiency have reached the international advanced level. Up to now, the first batch of 80 sets have been sent to Wuhan Huoshenshan Hospital, all installed in ICU, operating room and negative pressure ward. Shandong Henghao Information Technology Co., Ltd. urgently developed and released the public welfare software "New Crown Pneumonia Epidemic Management System" to the whole country, providing free cloud space and cloud services that can be operated by millions of users at the same time.
Zibo, Rizhao, Dongying, Binzhou and other municipal science and technology bureaus have taken action to formulate emergency plans, calling on science and technology enterprises and scientific and technological workers to take the initiative to assume social responsibility, provide support and help within their capacity, and contribute to winning the epidemic prevention and control war. Dongying Qirun Chemical Co., Ltd., located in the Yellow Triangle Nonggao District, donated 10 million yuan to support the epidemic prevention and control and the development of public health in the Yellow Triangle Nonggao District.
2. the province's relevant colleges and universities to quickly carry out emergency research, for the first line of anti-epidemic contribution of scientific and technological strength.
With the support of major scientific and technological innovation projects in the province, the Provincial Biodiagnostic Technology Innovation Center took the lead in breaking through the rapid detection technology of novel coronavirus antibodies, and developed the enzyme-linked immunosorbent assay novel coronavirus IgM antibody detection kit and IgG antibody detection kit. The detection cost is about 70% lower than the traditional detection price.
Qingdao Pilot National Laboratory of Marine Science and Technology has strengthened the research and development of blue drugs against novel coronavirus, carried out relevant molecular and cell measurement research work, and cooperated with Ocean University of China, Qingdao Marine Biomedical Research Institute, Sun Yat-sen University, Fudan University, Lanzhou University and Shandong First Medical University to identify 8 potential drug screening targets and build models that can be used for supercomputing screening, collecting more than 74000 compound information, among them, there are nearly 6000 natural product molecules derived from the ocean. More than 2000 seedling compounds were obtained, 26 of which have been verified by molecular dynamics simulation and have the potential to become drugs.
Taishan scholar distinguished expert, Linyi University professor Zhang Xinglin team developed the 2019 new coronavirus nucleic acid detection kit (multiple fluorescence PCR method) and other three new coronavirus nucleic acid detection kits, has passed the State Food and Drug Administration technical inspection, with simplified operation, stable results and other advantages. At present, the product has entered the clinical verification stage and has been included in the national rapid approval channel.
Ludong University uses nanomaterials, isothermal amplification, virus aerosol sampling and evaluation technologies to actively carry out a variety of pathogenic microorganism detection methods including coronavirus and environmental disinfection research, accumulating a large amount of data and research results, and assembling a fast and simple detection kit. The detection time limit of a single sample is as low as about 1 hour, which greatly shortens the detection time.
3. the provincial innovation and entrepreneurship community to highlight the responsibility as a strong scientific and technological backing to win the war of epidemic prevention and resistance.
Led by key medical device enterprises such as Boke Group and Weigao Group, the Shandong Biological Diagnostic Analysis Industry Innovation and Entrepreneurship Community and the Shandong High-end Medical Device Innovation and Entrepreneurship Community have stepped up the production of prevention and control medical products and medical devices. A total of new coronavirus infection in Shandong Province The leading group for the handling of pneumonia, Wuhan Sixth Hospital, Shandong Maternal and Child Health Hospital, Yangtze River Shipping General Hospital and other units, donated surgical gowns, disinfectants, infusion sets, syringes, masks and other medical materials with a total value of more than 800 million yuan, and continued to supply nearly 200 sets of safety cabinets, sterilizers, clean tables, disinfection machines and other equipment.
Shandong Traditional Chinese Medicine Industry Innovation and Entrepreneurship Community has set up a joint research team for novel coronavirus Chinese and western medicine adjuvant therapy series products, jointly developed Chinese and western medicine adjuvant therapy series products, launched the development and donation plan for new coronavirus Chinese and western medicine adjuvant therapy series products, organized and implemented and promoted rapidly according to the mode of "research and development-transformation-industry-promotion", and accelerated the integration and transformation of corresponding technologies into products and promotion to the market.
Shandong smart health innovation and entrepreneurship community around the virus kit development, inspection and testing, drug research and development, intelligent epidemic prevention equipment and other links to carry out scientific research. Its member unit Shandong Taibang Biological Products Co., Ltd. has resumed production in an emergency and has now raided the production of 8 batches of intravenous human immunoglobulin (2.5g/bottle), totaling more than 250000.
China Building Materials General Institute, a member of Shandong Inorganic Functional Materials and Intelligent Manufacturing Innovation and Entrepreneurship Community, organized its employees to overcome difficulties and return to work. After 7 days of overtime work, it has produced 600 sets of high-precision inorganic functional material infrared lenses, which have been applied to Guangzhou Baiyun Airport, Chengdu (East Station, North Station), Wuhan (Union Hospital) and other front-line epidemic screening.
In view of the increasing shortage of anti-epidemic materials such as medical masks and protective clothing, Shandong antibody drug innovation and entrepreneurship community organized Yantai yeda international biomedical innovation and incubation center co., ltd., a member unit of the community, to provide Yantai shulang medical technology co., ltd. with urgently needed production sites for production of protective products, including 875 square meters of grade d laboratories and 560 square meters of non-clean laboratories. At present, Shulang Company produces 2000 sets of medical protective clothing per day and continues to be transported to Wuhan.
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